Dental Research Today is a free monthly online journal that collates and summarizes the latest research about Dental, including details on implants, health, hygiene, cosmetic, dentistry. | ||||||||
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Roles of Different Areas of Palatine Bone Denudation on Growth and Development of the Maxilla and Dental Arch: An Experimental Study.Meng T, Shi B, Huang X, Zheng Q, Wang Y, Wu M, Lu Y, Li S From the *Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu, People's Republic of China; and †Department of Biochemistry and Molecular Biology, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota. This study was designed to explore the relationship of the growth of the maxilla and dental arch with different sizes of the denudation area on the hard palate. We tested the hypothesis that different sizes of denudation areas on the hard palate following palatoplasty would significantly influence the growth of the maxilla and dental arch differently. Fifty-one three-week-old Sprague-Dawley male rats were randomly divided into a control group and 3 experimental groups. In the three experimental groups, bilateral palatal mucoperiosteum was excised to three different proportions, i.e. one-quarter, one-half and three-quarters of the palate. Then, the animals were sequentially injected weekly with different fluorescent markers alternately. Three in each group were sacrificed randomly every two weeks with maxilla dissected following injections. The widths of the maxilla and dental arch were measured and the fluorescent labeling investigated at different phases. The results showed that the growth of the maxilla and dental arch here was inversely correlated with the area of denuded bone on palate. Therefore, our data may provide references for optimal treatment of cleft palate. Published 6 April 2007 in J Craniofac Surg, 18(2): 391-398.
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