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Biocompatibility of resin-based dental materials applied as liners in deep cavities prepared in human teeth.

de Souza Costa CA, Teixeira HM, Lopes do Nascimento AB, Hebling J

Araraquara School of Dentistry, University of São Paulo State-UNESP, Rua Humaitá, 1680 CEP: 14.801-903, CP: 331, Araraquara, São Paulo, Brazil. casouzac@foar.unesp.br

BACKGROUND: Since only a few data have been published concerning the effects of resinous dental materials on the pulp-dentin complex, the aim of this study was to evaluate the biocompatibility of resin-based materials applied as liners in deep cavities prepared in human teeth. METHODS: After preparing class V cavities, the following dental materials were applied on the axial walls: group 1, Vitrebond (VIT; 3M ESPE); group 2, Ultra-Blend Plus (UBP; Untradent); and group 3, Clearfil SE Bond (CSEB; Kuraray). In group 4 (control), the hard-setting calcium hydroxide cement Dycal (CH; Caulk/Dentsply) was used. The teeth extracted at 7 days or between 30 and 85 days after the clinical procedures were processed for histological evaluation. RESULTS: For all the experimental and control groups, most of specimens exhibited no pulpal response or slight inflammatory reaction associated with slight tissue disorganization at 7-day period. Moderate inflammatory pulpal response occurred only in one tooth (RDT = 262 microm) of group 3 in which transdentinal diffusion of resin components was observed. CONCLUSION: The resin-based dental cements VIT and UBP as well as the bonding agent CSEB presented acceptable biocompatibility when applied in deep cavities prepared in sound human teeth.

Published 7 March 2007 in J Biomed Mater Res B Appl Biomater, 81(1): 175-84.
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